AWWA ACE65466

This powerpoint presentation's research strategy was: to develop Physiologically Based Pharmacokinetic Model to quantify organ dose from ingestion and toxic responses at low dose; and, a mechanism of toxic response at low doses. This leads to: re-examination of basis for MCLG; and, revision of risk assessment at low doses. Topics covered include: Pre-systemic Decomposition; the importance of Bromate in Drinking Water to Water Suppliers; Bromate Health Risk Summary; Critical Risk Assessment Issues; Critical Risk Assessment Issues; Why Risk Assessment Matters; Previous Research; Bromate Chemistry and Kinetics; Bromate Research Program Overview; Model of Bromate Toxicokinetics; Transport and Decomposition in vivo; Where are we now-summary; and, Current Study-April 2007 to January 2009.